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Acid-Catalyzed Synthesis of Methylene-Bridged (S)-Tyrosine−Phenol Dimers

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journal contribution
posted on 29.09.2006, 00:00 by Sean P. Bew, David L. Hughes, Sunil V. Sharma
The efficient synthesis of 2,2‘-arylmethylene dimers from 3-hydroxymethyl or 3-methoxymethyl-5-halo-(S)-tyrosines and para-substituted phenols under acid-catalyzed reaction conditions using either conventional or microwave-assisted protocols is described.