American Chemical Society
jo9b00075_si_001.pdf (3.36 MB)

Achieving Nickel Catalyzed C–S Cross-Coupling under Mild Conditions Using Metal–Ligand Cooperativity

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journal contribution
posted on 2019-03-11, 00:00 authored by Rina Sikari, Suman Sinha, Siuli Das, Anannya Saha, Gargi Chakraborty, Rakesh Mondal, Nanda D. Paul
A simple and efficient approach of C–S cross-coupling of a wide variety of (hetero)­aryl thiols and (hetero)­aryl halides under mild conditions, mostly at room temperature, catalyzed by well-defined singlet diradical Ni­(II) catalysts bearing redox noninnocent ligands is reported. Taking advantage of ligand centered redox events, the high-energetic Ni(0)/Ni­(II) or Ni­(I)/Ni­(III) redox steps were avoided in the catalytic cycle. The cooperative participation of both nickel and the coordinated ligands during oxidative addition/reductive elimination steps allowed us to perform the catalytic reactions under mild conditions.