American Chemical Society
np070443h_si_002.pdf (2.44 MB)

Acanthosulfate, a Sulfated Hydroxyhydroquinone Sesterterpenoid from the Sponge Acanthodendrilla sp.

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journal contribution
posted on 2008-02-22, 00:00 authored by Lyndon M. West, D. John Faulkner
The marine sponge Acanthodendrilla sp. contains the proteasome inhibitor acanthosulfate (4), a disulfated merosesterterpene having a scalarane-type skeleton. The structure of acanthosulfate (4), which possesses an unusual configuration, was elucidated by interpretation of spectroscopic data.