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A Stereodivergent Approach to Amino Acids, Amino Alcohols, or Oxazolidinones of High Enantiomeric Purity

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journal contribution
posted on 05.08.2004, 00:00 by Claude Spino, Marie-Claude Tremblay, Cédrickx Gobdout
(−)-Menthone, an inexpensive chiral auxiliary, was used to prepare both enantiomers of α-amino acids, amino alcohols, or oxazolidinones. The sequence includes the SN2‘ displacement by a cuprate reagent and a Curtius rearrangement as key steps.