American Chemical Society
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A Short Synthesis of the Triazolopyrimidine Antibiotic Essramycin

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journal contribution
posted on 2010-11-29, 00:00 authored by Ugo Battaglia, Christopher J. Moody
A short synthesis of the 1,2,4-triazolo[1,5-a]pyrimidine antibiotic essramycin is described involving condensation of aminoguanidine with ethyl benzoylacetate to give an amino-1,2,4-triazole, followed by condensation with ethyl acetoacetate to form the pyrimidone ring.