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A Rapid Synthesis of Hexofuranose-like Iminosugars Using Ring-Closing Metathesis

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journal contribution
posted on 04.08.2005, 00:00 by Sylvaine Cren, Claire Wilson, Neil R. Thomas
Two new 1-N-iminosugars have been prepared as hexofuranose analogues in an efficient manner by an RCM-based route. Both 3,4-disubstituted pyrrolidines display moderate inhibitory activity against Mycobacterium smegmatis galactan biosynthesis.

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