ol034766q_si_001.pdf (48.09 kB)

A Novel Redox Reaction between 8-Aza-5,7-dimethyl-2-trifluoromethylchromone and Alkyl Mercaptoacetates

Download (48.09 kB)
journal contribution
posted on 06.06.2003, 00:00 by Vyacheslav Ya. Sosnovskikh, Mikhail A. Barabanov, Boris I. Usachev
8-Aza-5,7-dimethyl-2-trifluoromethylchromone reacts with alkyl mercaptoacetates to give pyrido derivatives of 2-oxa-7-thiabicyclo[3.2.1]octane, which undergo the reductive ring-opening to sulfanyl acetates. The latter compounds are useful CF3-containing building blocks for the preparation of a variety of 2-pyridone derivatives.

History

Exports