A New Fluorescent Chemodosimeter for Hg2+: Selectivity, Sensitivity, and Resistance to Cys and GSH

Du, Jianjun; Fan, Jiangli; Peng, Xiaojun; Sun, Pingping; Wang, Jingyun; Li, Honglin; Sun, Shiguo

doi:10.1021/ol902590g.s001

ol902590g_si_001.pdf (242.87 kB)

A New Fluorescent Chemodosimeter for Hg²⁺: Selectivity, Sensitivity, and Resistance to Cys and GSH

journal contribution

posted on 2010-02-05, 00:00 authored by Jianjun Du, Jiangli Fan, Xiaojun Peng, Pingping Sun, Jingyun Wang, Honglin Li, Shiguo Sun

On the basis of the mechanism of Hg²⁺-promoted hydrolysis, a new fluorescent chemodosimeter (Rho-Hg1) is reported for single-selective and parts per billion level-sensitive detection of Hg²⁺ in natural waters. Moreover, the fluorescence response of Rho-Hg1 to Hg²⁺ has little interference from sulfur compounds such as cysteine and glutathione and could be used in the Hg²⁺ imaging in living cells.