np990628r_si_001.pdf (108.45 kB)
A New 2D-TLC Bioautography Method for the Discovery of Novel Antifungal Agents To Control Plant Pathogens
journal contribution
posted on 2000-07-13, 00:00 authored by David E. Wedge, Dale G. NagleA new bioassay has been developed combining the simplicity of direct bioautography with the improved
chromatographic resolution of 2D-TLC. Mixtures of structurally diverse antifungal agents were tested to
establish the validity and utility of this method in the discovery of new natural products with activity
against agriculturally important fungal pathogens.