American Chemical Society
ol9b03258_si_001.pdf (1.03 MB)

A Multifunctional Hybrid[4]arene-Based Macrocyclic Amphiphile: Self-Assembly, Tunable LCST Behavior, and Construction of Fluorescent Nanoparticles for Cell Imaging

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journal contribution
posted on 2019-10-28, 13:06 authored by Ming Li, Hongzhen Bai, Li Shao, Bin Hua
A novel macrocyclic amphiphile based on hybrid[4]­arene containing tri­(ethylene glycol) chains as the hydrophilic part and benzene rings as the hydrophobic part was synthesized. It self-assembled to produce nanoparticles and showed lower critical solution temperature behavior that was affected by its concentration and K+. Moreover, amphiphilic H can encapsulate dye G to form host–guest complexes HG, accompanied by significant fluorescence enhancement. HG can further self-assemble to form fluorescent nanoparticles that can be applied in cell imaging.