A General Method for the Preparation of N-Sulfonyl Aldimines and Ketimines†
journal contributionposted on 20.01.2005, 00:00 by José Luis García Ruano, José Alemán, M. Belén Cid, Alejandro Parra
A simple procedure to obtain N-sulfonyl imines involving the condensation of carbonyl compounds with p-tolyl or tert-butyl sulfinamides followed by oxidation with m-CPBA of the resulting N-sulfinylimines is reported. The method is applicable to aldehydes (aliphatics and aromatics) and ketones (diaryl, dialkyl, and aryl alkyl), even those containing enolizable protons. It also does not affect CN or CC double bonds and does not epimerize α-stereogenic centers.