American Chemical Society
ja5b13173_si_001.pdf (1.23 MB)

A Dual-Thermoresponsive Gemini-Type Supra-amphiphilic Macromolecular [3]Pseudorotaxane Based on Pillar[10]arene/Paraquat Cooperative Complexation

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journal contribution
posted on 2016-02-10, 00:00 authored by Xiaodong Chi, Guocan Yu, Li Shao, Jianzhuang Chen, Feihe Huang
Herein, first we report the preparation of a thermoresponsive [3]­pseudorotaxane from cooperative complexation between a water-soluble pillar[10]­arene and a paraquat derivative in water. Then we successfully construct the first pillararene-based gemini-type supra-amphiphilic [3]­pseudorotaxane from the water-soluble pillar[10]­arene and a paraquat-containing poly­(N-isopropylacrylamide) based on this new molecular recognition motif in water. This macromolecular [3]­pseudorotaxane shows unique dual-thermoresponsiveness. Furthermore, it can self-assemble into polymeric vesicles at 37 °C in water. These vesicles can be further used in the controlled release of small molecules induced by cooling to 25 °C or heating to 60 °C.