A Convergent Synthesis of the C1−C16 Segment of Goniodomin A via Palladium-Catalyzed Organostannane−Thioester Coupling

Fuwa, Haruhiko; Nakajima, Motohiro; Shi, Jinglu; Takeda, Yoshiyuki; Saito, Tomoyuki; Sasaki, Makoto

doi:10.1021/ol1031409.s001

A Convergent Synthesis of the C1−C16 Segment of Goniodomin A via Palladium-Catalyzed Organostannane−Thioester Coupling

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posted on 2011-03-04, 00:00 authored by Haruhiko Fuwa, Motohiro Nakajima, Jinglu Shi, Yoshiyuki Takeda, Tomoyuki Saito, Makoto Sasaki

A convergent synthesis of the C1−C16 segment of goniodomin A, an actin-targeting marine polyether macrolide natural product, has been achieved via a 2-fold application of palladium-catalyzed organostannane−thioester coupling.

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organostannane convergent application synthesis Goniodomin polyether marine Organostannane goniodomin macrolide CouplingA Convergent Synthesis

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A Convergent Synthesis of the C1−C16 Segment of Goniodomin A via Palladium-Catalyzed Organostannane−Thioester Coupling

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