posted on 2011-12-16, 00:00authored byPeijun Liu, Juan Wang, Jiancun Zhang, Fayang G. Qiu
A concise total synthesis of (±)-minfiensine using all conventional methods and starting from commercial materials has been completed. The synthesis features a Fischer indole synthesis, a Heck alkylation of an intermediate ketone enolate, conversion of a ketone carbonyl into an epoxide, and transformation of the latter into an allylic alcohol.