American Chemical Society
ol2027224_si_001.pdf (14.99 MB)

A Concise Total Synthesis of (±)-Minfiensine

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journal contribution
posted on 2011-12-16, 00:00 authored by Peijun Liu, Juan Wang, Jiancun Zhang, Fayang G. Qiu
A concise total synthesis of (±)-minfiensine using all conventional methods and starting from commercial materials has been completed. The synthesis features a Fischer indole synthesis, a Heck alkylation of an intermediate ketone enolate, conversion of a ketone carbonyl into an epoxide, and transformation of the latter into an allylic alcohol.