posted on 2020-03-20, 14:39authored byAmanda Acevedo-Jake, Andrew T. Ball, Marzia Galli, Mikiembo Kukwikila, Mathieu Denis, Daniel G. Singleton, Ali Tavassoli, Stephen M. Goldup
We
present a simple strategy for the synthesis of main chain oligonucleotide
rotaxanes with precise control over the position of the macrocycle.
The novel DNA-based rotaxanes were analyzed to assess the effect of
the mechanical bond on their properties.