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3,3-Difluoro-1-iodocyclopropenes:  A Simple Synthesis and Their Reactions

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journal contribution
posted on 27.11.2002, 00:00 by Wei Xu, Qing-Yun Chen
The [1 + 2] cycloaddition reaction of 1-iodoalkynes with difluorocarbene, generated from the decomposition of FSO2CF2COOSiMe3 in diglyme in the presence of 10 mol % NaF at 120 °C, gives 3,3-difluoro-1-iodocyclopropenes in good yields. These new iodides can be trifluoromethylated and functionalized via the Heck reaction. The unusual hydrolytic reactions of the iodides under acidic conditions was also investigated.