1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2-
phenylpropan-1-ones:  Mosher-Bt Reagents

Katritzky, Alan R.; Mohapatra, Prabhu P.; Fedoseyenko, Dmytro; Duncton, Matthew; Steel, Peter J.

doi:10.1021/jo070278a.s002

1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2- phenylpropan-1-ones: Mosher-Bt Reagents

journal contribution

posted on 2007-05-25, 00:00 authored by Alan R. Katritzky, Prabhu P. Mohapatra, Dmytro Fedoseyenko, Matthew Duncton, Peter J. Steel

Benzotriazole derivatives of 3,3,3-trifluoro-2-methoxy-2-phenylpropionic acid react with water-soluble amino acids and peptides in an acetonitrile/water (2:1) mixture to give the corresponding amides in quantitative yield.

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ReagentsBenzotriazole acid peptide trifluoro amide phenylpropan acetonitrile mixture derivative Benzotriazol

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1-Benzotriazol-1-yl-3,3,3-trifluoro-2-methoxy-2- phenylpropan-1-ones: Mosher-Bt Reagents

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