Use of Conjugated Dienones in Cyclialkylations: Total Syntheses of Arucadiol, 1,2-Didehydromiltirone, (±)-Hinokione, (±)-Nimbidiol, Sageone, and Miltirone†
journal contributionposted on 03.10.1997 by George Majetich, Shuang Liu, Jing Fang, David Siesel, Yong Zhang
Any type of content formally published in an academic journal, usually following a peer-review process.
Functionalized hydrophenanthrenes can be prepared using a cyclialkylation-based strategy. These annulations are highly dependent on the directing effects of the arene substitutents and on conformational considerations. The utility of this methodology was featured in the syntheses of six diterpenoids.