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Triterpene Saponins from Gynostemma cardiospermum

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journal contribution
posted on 27.10.2006 by Feng Yin, Yinan Zhang, Zhengyi Yang, Qiuqun Cheng, Lihong Hu
Six new dammarane glycosides (16) and four known compounds, rutin, kaempferol, quercetin, and linalool 3-O-β-d-glucopyranoside, were isolated from an ethanol extract of the aerial parts of Gynostemma cardiospermum. The structures of 16 were elucidated by 1D and 2D NMR spectroscopic interpretation as well as by chemical degradation. Triterpene aglycons containing carbonyl groups at both C-21 and C-28, as found in compounds 15, are being reported in the family Cucurbitaceae for the first time.