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Total Synthesis of the Marine Cyclic Depsipeptide Viequeamide A

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journal contribution
posted on 24.05.2013, 00:00 by Dongyu Wang, Shanshan Song, Ye Tian, Youjun Xu, Zehong Miao, Ao Zhang
The first total synthesis of viequeamide A, a natural cyclic depsipeptide isolated from a marine button cyanobacterium, was achieved with the N-Me-Val–Thr peptide bond as the final macrocyclization site. The synthetic product gave nearly identical spectroscopic data to that reported for the natural product.