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Total Synthesis of cis- and trans-3-Hydroxy-d-proline and (+)-Detoxinine

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journal contribution
posted on 26.01.1996, 00:00 by Johann Mulzer, Andreas Meier, Jürgen Buschmann, Peter Luger
The unnatural enantiomer of the amino acid detoxinine and both diastereomeric 3-hydroxy-d-prolines have been prepared from d-mannitol via the O-silylated hydroxyproline 12 as a common key intermediate.