Three New Scalarane Sesterterpenoids from the Okinawan Sponge Hyrtios erectus
journal contributionposted on 31.08.2000 by Hiroaki Miyaoka, Satoshi Nishijima, Hidemichi Mitome, Yasuji Yamada
Any type of content formally published in an academic journal, usually following a peer-review process.
Three new scalarane sesterterpenoidshyrtiolide (1), 16-hydroxyscalarolide (2), and 12-deacetyl-Δ17-hyrtial (3), were isolated from Okinawan sponge Hyrtios erectus, along with scalarolide (4) and 12-deacetylhyrtial (5). The structures of new compounds 1−3 were determined by spectroscopic analysis and chemical conversions. Compounds 3 and 5 showed antiproliferative activity toward KB cells.