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Synthesis of d-erythro-Dihydrosphingosine and d-xylo-Phytosphingosine from a Serine-Derived 1,5-Dioxaspiro[3.2]hexane Template

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journal contribution
posted on 18.04.2002 by Albert J. Ndakala, Mehrnoosh Hashemzadeh, Regina C. So, Amy R. Howell
A serine-derived 1,5-dioxaspiro[3.2]hexane template is shown to be a useful precursor for both aminodiol and aminotriol sphingoid bases by its conversion to d-erythro-dihydrosphingosine and d-xylo-phytoshingosine.