Synthesis of New DPP‑4 Inhibitors Based on a Novel Tricyclic Scaffold
journal contributionposted on 12.03.2015 by Carolin Schwehm, Jin Li, Hongmei Song, Xiao Hu, Barrie Kellam, Michael J. Stocks
Any type of content formally published in an academic journal, usually following a peer-review process.
A novel molecular scaffold has been synthesized, and its synthesis and incorporation into new analogues of biologically active molecules will be discussed. A comparison of the inhibitory activity of these compounds to the known type-2 diabetes compound (sitagliptin) against dipeptidyl peptidase-4 (DPP-4) will be shown.