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Synthesis and Characterization of Platinum(II) Complexes of l-Ascorbic Acid. Crystal Structure of Ascorbato-C2,O5-ethylenediamineplatinum(II) Dihydrate

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journal contribution
posted on 23.11.1999, 00:00 by Malcolm J. Arendse, Gordon K. Anderson, Nigam P. Rath
Reactions between diaminediaquaplatinum complexes [Pt(NN)(H2O)2]2+ and sodium ascorbate (NaHAsc) have been studied using 1H and 195Pt NMR spectroscopy. Mixtures of platinum ascorbate species were formed involving different binding modes of the ascorbate ligand, namely, [Pt(HAsc-O3)(H2O)(NN)]+, in which a single ascorbate acts as a monodentate ligand, the bis(ascorbate)platinum complexes [Pt(HAsc-O3)2(NN)] and [Pt(HAsc-O3)(HAsc-C2)(NN)], and [Pt(Asc-O2,O3)(NN)] and [Pt(Asc-C2,O5)(NN)], in which the ascorbate acts as a chelating ligand (NN = en, N,N-dmen, N,N‘-dmen, N,N,N,N‘-tmen; HAsc- = C6H7O6-, Asc2- = C6H6O62-). The crystal structure of ascorbato-C2,O5-ethylenediamineplatinum(II) dihydrate, [Pt(Asc-C2,O5)(en)]·2H2O, was established by X-ray crystallography. A series of diphosphineplatinum complexes of the type [Pt(Asc-O2,O3)(PP)] (PP = dppm, dppe, dppp) was prepared from the corresponding [Pt(NO3)2(PP)] species. These have been characterized by elemental analysis and infrared and 1H and 31P{1H} NMR spectroscopies.