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Substitution of Hydroxyl Groups with Alkynyl Moieties Using Alkynylboron Dihalides:  An Efficient Approach to Secondary Alkylacetylene Derivatives

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journal contribution
posted on 02.03.2006 by George W. Kabalka, Min-Liang Yao, Scott Borella
The reaction of alkynylboron dihalides with benzylic, allylic, and propargylic alcohols provides an efficient route to internal acetylenes. Isomerization of the product alkynes does not occur under the reaction conditions.