Substitution of Hydroxyl Groups with Alkynyl Moieties Using Alkynylboron Dihalides: An Efficient Approach to Secondary Alkylacetylene Derivatives
journal contributionposted on 02.03.2006 by George W. Kabalka, Min-Liang Yao, Scott Borella
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The reaction of alkynylboron dihalides with benzylic, allylic, and propargylic alcohols provides an efficient route to internal acetylenes. Isomerization of the product alkynes does not occur under the reaction conditions.