Resveratrol Oligomers from Vatica albiramis
journal contributionposted on 24.09.2010 by Naohito Abe, Tetsuro Ito, Kenji Ohguchi, Minori Nasu, Yuichi Masuda, Masayoshi Oyama, Yoshinori Nozawa, Masafumi Ito, Munekazu Iinuma
Any type of content formally published in an academic journal, usually following a peer-review process.
Five new stilbenoids, vatalbinosides A−E (1−5), and 13 known compounds (6−18) were isolated from the stem of Vatica albiramis. The effects of these new compounds on interleukin-1β-induced production of matrix metalloproteinase-1 (MMP-1) in human dermal fibroblasts were examined. Three resveratrol tetramers, (−)-hopeaphenol (6), vaticanol C (13), and stenophyllol C (14), were identified as strong inhibitors of MMP-1 production.