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Prenylbicyclogermacrane Diterpenoids from the Formosan Soft Coral Nephthea pacifica

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journal contribution
posted on 28.01.2005 by Ali A. H. El-Gamal, Shang-Kwei Wang, Chang-Feng Dai, I-Gin Chen, Chang-Yih Duh
Ten new prenylbicyclogermacrane diterpenoids, pacificins A−J (110), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.