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Polyacetylenes from a Red Sea Sponge Callyspongia Species

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journal contribution
posted on 04.10.2000 by Diaa T. A. Youssef, Wesley Y. Yoshida, Michelle Kelly, Paul J. Scheuer
From the methanolic extract of the Red Sea sponge Callyspongia sp. six new polyacetylenic compounds, aikupikanynes A−F, together with octahydrosiphonochalyne, were isolated and identified. Their structures, which comprise four hydrocarbons, two alcohols, and one unprecedented α-hydroxy carboxylic acid, were determined by extensive 1D and 2D NMR studies and mass spectral determinations.