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Phenolic and Triterpene Glycosides from the Stems of Ilex litseaefolia

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journal contribution
posted on 28.10.2005, 00:00 by Ai-Lian Zhang, Qi Ye, Bo-Gang Li, Hua-Yi Qi, Guo-Lin Zhang
Chemical investigation on the stems of Ilex litseaefolia afforded four new phenolic glycosides, litseaefolosides A−D (14), and two new triterpene glycosides, spathodic acid 28-O-β-d-glucopyranoside (5) and (20S)-niga-ichigoside F1 (6), along with 28 known compounds. The structures of 16 were determined on the basis of chemical and spectroscopic evidence. Litseaefoloside C (3) showed inhibitory activities in vitro for α-glucosidase and lipase with IC50 values of 34.0 and 0.31 μg/mL, respectively.