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Palladium(0)-Catalyzed Highly Regio- and Stereoselective Addition of Organoboronic Acids with 1,2-Allenylphosphonates Forming Tri- or Tetrasubstituted 1(E)-Alkenylphosphonates

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journal contribution
posted on 18.08.2006, 00:00 by Shengming Ma, Hao Guo, Fei Yu
A highly regio- and stereoselective palladium(0)-catalyzed addition of organoboronic acids with 1,2-allenylphosphonates in the presence of HOAc forming tri- or tetrasubstituted 1(E)-alkenylphosphonates is reported in this paper. The stereoselectivity is much higher than the reported cases. The effects of different R1, R2, and R3 were studied. A mechanism of this reaction is proposed on the basis of our previous study.