Palladium-Catalyzed Hydrocarbonylative Cyclization of 1,5-Dienes
journal contributionposted on 06.08.2019 by Suchen Zou, Bao Gao, Yao Huang, Tianze Zhang, Hanmin Huang
Any type of content formally published in an academic journal, usually following a peer-review process.
A novel and atom-economic palladium-catalyzed isomerization-hydrocarbonylative cyclization reaction of 1,5-dienes to 2-alkylidenecyclopentanones has been developed, which provides a rapid and straightforward approach to 2-alkylidenecyclopentanones with high stereoselectivity. The reaction was found to proceed via alkene isomerization and selective hydrocarbonylative cyclization to generate 2-alkylidenecyclopentanones with high selectivity.