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One-Pot Synthesis of Xanthones and Thioxanthones by the Tandem Coupling−Cyclization of Arynes and Salicylates

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journal contribution
posted on 15.09.2005 by Jian Zhao, Richard C. Larock
The reaction of silylaryl triflates, CsF, and salicylates affords a general and efficient way to prepare biologically interesting xanthones and thioxanthones. This chemistry presumably proceeds by a tandem intermolecular nucleophilic coupling and subsequent intramolecular electrophilic cyclization.