Isoprenylated Flavonoids and Adipogenesis-Promoting Constituents from Morus nigra
journal contributionposted on 25.04.2011 by Xiao Hu, Jin-Wei Wu, Xiao-Dong Zhang, Qin-Shi Zhao, Jian-Ming Huang, He-Yao Wang, Ai-Jun Hou
Any type of content formally published in an academic journal, usually following a peer-review process.
Ten new isoprenylated flavonoids, nigrasins A−J (1−10), and three known compounds were isolated from the twigs of Morus nigra. Compounds 8 and 9 promoted adipogenesis, characterized by increased lipid droplet and triglyceride content in 3T3L1 cells, and induced up-regulation of the expression of adipocyte-specific genes, aP2 and GLUT4.