Iron-Catalyzed Suzuki−Miyaura Coupling of Alkyl Halides
journal contributionposted on 11.08.2010 by Takuji Hatakeyama, Toru Hashimoto, Yoshiyuki Kondo, Yuichi Fujiwara, Hirofumi Seike, Hikaru Takaya, Yoshinori Tamada, Teruo Ono, Masaharu Nakamura
Any type of content formally published in an academic journal, usually following a peer-review process.
In the presence of novel iron(II) chloride−diphosphine complexes and magnesium bromide, lithium arylborates react with primary and secondary alkyl halides to give the corresponding coupling products in good to excellent yields. High functional group compatibility is also demonstrated in the reactions of substrates possessing reactive substituents, such as alkoxycarbonyl, cyano, and carbonyl groups.