ol802651b_si_001.pdf (963.33 kB)

Homologation of Boronic Esters with Lithiated Epoxides for the Stereocontrolled Synthesis of 1,2- and 1,3-Diols and 1,2,4-Triols

Download (963.33 kB)
journal contribution
posted on 01.01.2009 by Emeline Vedrenne, Olov A. Wallner, Maxime Vitale, Frank Schmidt, Varinder K. Aggarwal
Lithiated epoxides react stereospecifically with boronic esters to give syn-1,2-diols, a process that can be used iteratively to create triols containing four stereogenic centers.