Generation, Characterization, and Application of Hierarchically Structured Self-Assembly Induced by the Combined Effect of Self-Emulsification and Phase Separation
journal contributionposted on 02.02.2016 by Xiuyu Wang, Yi Hou, Li Yao, Mingyuan Gao, Maofa Ge
Any type of content formally published in an academic journal, usually following a peer-review process.
Hierarchically structured magnetic single-hole hollow spheres (MSHS) have been successfully obtained via a facile self-assembly strategy. This methodology allows the double emulsions generated via the combined effect of self-emulsification and phase separation to provide confinement for directing the self-assembly of magnetic nanoparticles (MNPs). The resulting MSHS fully capitalize on both the multifunctional properties of MNPs and container features of single-hole hollow spheres. Moreover, the magnetic properties showed obvious improvement and can be tuned by modulating the assembled structure. Thus, MSHS can be used as a smart platform with multiple functionalities including image contrast enhancement, selective encapsulation for biomacromolecules, on-demand release, and magnetically guided transport. This strategy is very promising in the design of hierarchically structured assemblies for desired applications in biomedicine and other fields.