ol062943s_si_001.pdf (449.04 kB)

First Protection of a Wide-Rim Tetraamino Calix[4]arene in Opposite Positions

Download (449.04 kB)
journal contribution
posted on 15.03.2007 by Yuliya Rudzevich, Valentyn Rudzevich, Dieter Schollmeyer, Volker Böhmer
The importance of tetraamino calix[4]arenes as starting materials is distinctly increased by the first versatile protective group for opposite amino functions. Reaction with trityl chloride leads to the 1,3-dialkylated derivative easily isolated in 34% yield; after a first acylation of the remaining amino groups, the trityl residues can be removed by TFA to introduce a second acyl group.