First Protection of a Wide-Rim Tetraamino Calixarene in Opposite Positions
journal contributionposted on 15.03.2007 by Yuliya Rudzevich, Valentyn Rudzevich, Dieter Schollmeyer, Volker Böhmer
Any type of content formally published in an academic journal, usually following a peer-review process.
The importance of tetraamino calixarenes as starting materials is distinctly increased by the first versatile protective group for opposite amino functions. Reaction with trityl chloride leads to the 1,3-dialkylated derivative easily isolated in 34% yield; after a first acylation of the remaining amino groups, the trityl residues can be removed by TFA to introduce a second acyl group.