Enantioselective Syntheses of Furan Atropisomers by an Oxidative Central-to-Axial Chirality Conversion Strategy
journal contributionposted on 20.01.2017, 00:00 by Vivek S. Raut, Marion Jean, Nicolas Vanthuyne, Christian Roussel, Thierry Constantieux, Cyril Bressy, Xavier Bugaut, Damien Bonne, Jean Rodriguez
Any type of content formally published in an academic journal, usually following a peer-review process.
For the first time, enantiomerically enriched atropoisomeric furans have been accessed using a central-to-axial chirality conversion strategy. Hence, oxidation of the enantioenriched dihydrofuran precursors gave rise to axially chiral furans with high enantiopurities accounting from excellent conversion percentages (cp) in most cases.