Enamide-Benzyne-[2 + 2] Cycloaddition: Stereoselective Tandem [2 + 2]−Pericyclic Ring-Opening−Intramolecular N-Tethered [4 + 2] Cycloadditions
journal contributionposted on 20.08.2009 by John B. Feltenberger, Ryuji Hayashi, Yu Tang, Eric S. C. Babiash, Richard P. Hsung
Any type of content formally published in an academic journal, usually following a peer-review process.
Benzyne-[2 + 2] cycloadditions with enamides are described. This effort led to the development of a highly stereoselective tandem [2 + 2] cycloaddition−pericyclic ring-opening−intramolecular-N-tethered-[4 + 2] cycloaddition for rapid assembly of nitrogen heterocycles.