Efficient NO Equivalent for Activation of Molecular Oxygen and Its Applications in Transition-Metal-Free Catalytic Aerobic Alcohol Oxidation
journal contributionposted on 25.05.2007 by Yi Xie, Weimin Mo, Dong Xu, Zhenlu Shen, Nan Sun, Baoxiang Hu, Xinquan Hu
Any type of content formally published in an academic journal, usually following a peer-review process.
tert-Butyl nitrite (TBN) was identified as an efficient NO equivalent for the activation of molecular oxygen. The unique property of TBN enabled TEMPO-catalyzed aerobic alcohol oxidation to be performed in high-volume efficiency. Up to a 16 000 turnover number was achieved in this transition-metal-free aerobic catalytic system. Under the optimal reaction conditions, various alcohols were converted into their corresponding carbonyl compounds with TEMPO/HBr/TBN as catalyst. The newly developed method was suitable for the oxidation of solid substrate alcohols with high melting point and/or low solubility under the help of minimum solvent to form a slurry.