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Design and Investigation of a Series of Rhodamine-Based Fluorescent Probes for Optical Measurements of pH

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journal contribution
posted on 16.07.2010, 00:00 by Quinn A. Best, Ruisong Xu, Matthew E. McCarroll, Lichang Wang, Daniel J. Dyer
A series of structurally similar fluorescent probes (14), synthesized from rhodamine B, were designed to optically measure pH. Each probe had a unique “off−on” response as the solution went from basic to acidic. Probes 13 exhibited a spirocyclic quenching of the pyronin B fluorophore, whereas probe 4 was quenched by PET from the amine moiety.