Cycloisomerization of Allene–Enol Ethers under Bi(OTf)3 Catalysis
journal contributionposted on 20.02.2015 by Pierrick Ondet, Amélie Joffrin, Ilhem Diaf, Gilles Lemière, Elisabet Duñach
Any type of content formally published in an academic journal, usually following a peer-review process.
The cycloisomerization of allene–enol ethers under Bi(OTf)3 catalysis was developed as a novel “atom-economic” tool for accessing interesting functionalized cyclopentene rings. Bi(OTf)3 was shown to promote selectively the activation of the enol ether moiety of the substrate. This catalytic methodology was further extended to the synthesis of dihydrofuran and oxaspirocycle derivatives.