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Copper-Mediated Reaction of Zirconacyclopentadienes with Azides: A One-Pot Three-Component Synthesis of Multiply Substituted Pyrroles from One Azide and Two Alkynes

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journal contribution
posted on 11.11.2013 by Yiqing Zhou, Xiaoyu Yan, Chao Chen, Chanjuan Xi
A general method for the synthesis of multiply substituted pyrroles through zirconocene-mediated coupling of two alkynes and an azide in the presence of CuCl has been achieved.