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Combining a Droplet-Based Microfluidic Tubing System with Gated Indicator Releasing Nanoparticles for Mercury Trace Detection

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posted on 10.02.2016 by Jérémy Bell, Estela Climent, Mandy Hecht, Merwe Buurman, Knut Rurack
A droplet-based microfluidic sensor was developed for the detection of Hg2+ traces in water. The approach uses gated mesoporous nanoparticles loaded with a fluorescent BODIPY dye. The squaraine-based gating mechanism is highly selective for Hg2+ and the indicator release mechanism ensures sensitive detection. The microfluidic system is modular and was assembled from simple PTFE/PFA tubes, while detection was realized with standard optomechanic, optic, and electronic parts. The sensor shows a stable response without memory effects and allows the detection of Hg2+ in water down to 20 ppt.

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