Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides
journal contributionposted on 17.08.2012 by Ke Gao, Pin-Sheng Lee, Chong Long, Naohiko Yoshikai
Any type of content formally published in an academic journal, usually following a peer-review process.
An ortho-arylation reaction of aromatic imines with aryl chlorides has been achieved using a cobalt–N-heterocyclic carbene catalyst in combination with a neopentyl Grignard reagent. The reaction takes place at room temperature to afford biaryl products in moderate to good yields.