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Chemo- and Regioselective Magnesium-Catalyzed ortho-Alkenylation of Anilines

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journal contribution
posted on 31.10.2019 by Adisak Chatupheeraphat, Magnus Rueping, Marc Magre
A simple and efficient catalytic system for a chemo- and regioselective ortho-alkenylation of anilines is presented. The new magnesium-catalyzed reaction allows the use of a wide range of alkynes and anilines with different electronic and steric properties and provides free as well as protected anilines with excellent yields.