Cellular Uptake of PNA−Terpyridine Conjugates and Its Enhancement by Zn2+ Ions
journal contributionposted on 10.05.2006 by Andreas Füssl, Andreas Schleifenbaum, Mareike Göritz, Andrew Riddell, Carsten Schultz, Roland Krämer
Any type of content formally published in an academic journal, usually following a peer-review process.
Conjugation of usually impermeable peptide nucleic acids (PNA) to the chelator 2,2‘:6‘,2‘ ‘-terpyridine strongly promotes cellular and nuclear uptake by cultured HeLa cells. Cellular accumulation is further enhanced in the presence of extracellular Zn2+.