Border Control in Hepatitis C Virus Infection: Inhibiting Viral Entry
journal contributionposted on 11.09.2015 by Cameron J. Schweitzer, T. Jake Liang
Any type of content formally published in an academic journal, usually following a peer-review process.
A new era has begun in the treatment of hepatitis C virus (HCV) infection with powerful yet expensive therapies. New treatments are emerging that target the entry step of HCV and could potentially block reinfection after liver transplant. These treatments include antibodies, which target the virus or host receptors required by HCV. Additionally, several new and previously approved small-molecule compounds have been described that target unique aspects of HCV entry. Overall, the blocking entry represents an attractive strategy that could yield powerful combination therapies to combat HCV.