Borane-Catalyzed Transfer Hydrogenations of Pyridines with Ammonia Borane
journal contributionposted on 28.09.2016 by Qiwen Zhou, Lanqiong Zhang, Wei Meng, Xiangqing Feng, Jing Yang, Haifeng Du
Any type of content formally published in an academic journal, usually following a peer-review process.
With the use of ammonia borane as a hydrogen source, a borane catalyzed metal-free transfer hydrogenation of pyridines was successfully realized for the first time to furnish a variety of piperidines in 44–88% yields with moderate to excellent cis-selectivities. The ease in handling without requiring high pressure H2 makes this transfer hydrogenation practical and useful.